Our research team is developing Salud!, an open and free infrastructure for developing and deploying personal health informatics applications. In addition, we are investigating and designing interaction techniques that support individuals engaged in health self-management. These interaction techniques make use of personal informatics applications’ potential to guide users through experiences of personal mastery, which are an effective method for increasing self-efficacy—a key factor in the success of self-management efforts. The goals of this position paper are two-fold: (1) to present the Salud! infrastructure and invite interested researchers from the personal informatics community to make use of this resource; and (2) to initiate a discussion about how personal informatics applications could support goal management for those users for whom such functionality would be desirable.